Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284695 | 0.82 | TDP1 (0.51) | ALDH1A1GAAGFERKMT2AMEN1 | |
| SCHEMBL9662788 | 0.81 | CYP2C9 (0.48) | ALDH1A1GAAGFERKMT2AMEN1 | |
| SCHEMBL3186556 | 0.80 | CYP2C9 (0.51) | ALDH1A1GAAGFERKMT2AMEN1 | |
| SCHEMBL3176961 | 0.79 | LMNA (0.55) | ALDH1A1GAAKMT2ATDP1LMNA | |
| SCHEMBL3263302 | 0.72 | LMNA (0.54) | ALDH1A1GAAGFERCA2CA9 | |
| SCHEMBL13789387 | 0.69 | KDM4E (0.50) | ALDH1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL15830106 | 0.68 | KEAP1 (0.54) | ALDH1A1GAAGFERCA2CA9 | |
| SCHEMBL26053782 | 0.68 | KMT2A (0.72) | ALDH1A1KMT2AMEN1TDP1NFKBIA | |
| SCHEMBL26053720 | 0.67 | TDP1 (0.70) | ALDH1A1KMT2AMEN1TDP1NFKBIA | |
| SCHEMBL12050283 | 0.66 | LMNA (0.64) | ALDH1A1KMT2AMEN1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511791-A2 | Pyrrolopyridine derivatives as Angiotensin inhibitors | ZENECA LIMITED (GB) | 1992-11-04 | — | — | EP | disclosed |