Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825301 | 0.86 | TSHR (0.48) | CYP19A1APPBACE1HPGDSIDO1 | |
| SCHEMBL28040113 | 0.81 | KDM4E (0.42) | CYP19A1APPBACE1HPGDSIDO1 | |
| SCHEMBL2260831 | 0.80 | GSK3A (0.48) | HPGDSIDO1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL2263350 | 0.80 | CNR1 (0.48) | HPGDSSMN1; SMN2LMNAGSK3AGSK3B | |
| SCHEMBL5448832 | 0.79 | ESR2 (0.56) | CYP19A1CYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL5535418 | 0.79 | PGR (0.46) | APPBACE1HPGDSSMN1; SMN2LMNA | |
| SCHEMBL4428277 | 0.77 | NOTUM (0.48) | BACE1SMN1; SMN2LMNAGSK3AGSK3B | |
| SCHEMBL2261486 | 0.76 | KDM4E (0.71) | SMN1; SMN2LMNAGSK3AGSK3BALDH1A1 | |
| SCHEMBL10430575 | 0.76 | KMT2A (0.49) | SMN1; SMN2LMNAGSK3AGSK3BALDH1A1 | |
| SCHEMBL6285893 | 0.74 | ALDH1A1 (0.50) | HPGDSSMN1; SMN2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500824-A1 | POLYMERS FOR SCAVENGING NITROSATING AGENTS | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5087671-A | Insoluble polymers containing reactive groups | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1992-02-11 | — | — | US | disclosed |
| WO-1992000122-A1 | POLYMERS FOR SCAVENGING NITROSATING AGENTS | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1992-01-09 | — | — | WO | disclosed |