Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976422 | 0.88 | CA1 (0.47) | KMT2AALDH1A1CYP1A2L3MBTL1PTGS1 | |
| SCHEMBL8568940 | 0.88 | ALDH1A1 (0.47) | KMT2AALDH1A1TSHRKDM1AHSD17B10 | |
| SCHEMBL30574489 | 0.87 | CYP2C19 (0.44) | KMT2AALDH1A1CYP3A4 | |
| SCHEMBL15670602 | 0.87 | KMT2A (0.47) | KMT2AALDH1A1 | |
| SCHEMBL29975235 | 0.87 | CASP1 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL3921752 | 0.87 | KMT2A (0.43) | KMT2AALDH1A1TSHRKDM1AHSD17B10 | |
| SCHEMBL15670601 | 0.87 | KMT2A (0.47) | KMT2AALDH1A1 | |
| SCHEMBL1159853 | 0.87 | CASP1 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL21296572 | 0.87 | CYP2C19 (0.44) | KMT2AALDH1A1CYP3A4 | |
| SCHEMBL29557046 | 0.87 | CASP1 (0.44) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138015-A | Reacting dialkyl carbonate with diamine to give urethane, thermally decomposing into diisocyanate, coverting into polyurethane in presence of Lewis acid and/or protonic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0477376-A1 | PROCESS FOR PRODUCING POLYURETHANE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-01 | — | — | EP | disclosed |