Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 12/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626277 | 0.88 | KDM4E (0.58) | KMT2ATOP2ATOP1TOP2BKDM4E | |
| SCHEMBL29080644 | 0.88 | KDM4E (0.58) | KMT2ATOP2ATOP1TOP2BKDM4E | |
| SCHEMBL9663694 | 0.88 | KMT2A (0.47) | KMT2ATOP2ATOP1TOP2BKDM4E | |
| SCHEMBL9869658 | 0.88 | KMT2A (0.69) | KMT2ATOP2ATOP1TOP2BALDH1A1 | |
| SCHEMBL9023293 | 0.87 | KMT2A (0.51) | KMT2ATOP2ATOP1TOP2BKDM4E | |
| SCHEMBL9869272 | 0.86 | TOP1 (0.54) | KMT2ATOP2ATOP1TOP2BKDM4E | |
| SCHEMBL9870457 | 0.86 | KMT2A (0.53) | KMT2ATOP2ATOP1TOP2BKDM4E | |
| SCHEMBL9665905 | 0.86 | LMNA (0.56) | KMT2ATOP2ATOP1TOP2BKDM4E | |
| SCHEMBL9870380 | 0.84 | KDM4E (0.64) | KMT2ATOP2ATOP1TOP2BKDM4E | |
| SCHEMBL9870058 | 0.84 | KMT2A (0.51) | KMT2ATOP2ATOP1TOP2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500835-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE. | DAE WOONG PHARMA (KR) | 1992-09-02 | — | — | EP | claimed |
| WO-1992004342-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1992-03-19 | — | — | WO | claimed |
| EP-0500835-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE. | DAE WOONG PHARMA (KR) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004342-A1 | A NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1992-03-19 | — | — | WO | disclosed |