Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 8/20 | 0.44 |
| ▸ | NOS1 | P29475 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772762 | 0.80 | HTT (0.58) | NOS2HTTNOS3NOS1MAPK1 | |
| SCHEMBL6765287 | 0.77 | NOS2 (0.38) | NOS2HTTNOS3NOS1 | |
| SCHEMBL9313998 | 0.77 | NOS2 (0.54) | NOS2NOS3NOS1 | |
| SCHEMBL9254075 | 0.75 | NOS2 (0.53) | NOS2NOS3NOS1 | |
| SCHEMBL10144472 | 0.75 | NOS2 (0.52) | NOS2NOS3NOS1 | |
| SCHEMBL13040577 | 0.74 | NOS2 (0.68) | NOS2NOS3NOS1 | |
| SCHEMBL15470594 | 0.74 | NOS2 (0.46) | NOS2NOS3NOS1 | |
| SCHEMBL11699836 | 0.74 | NOS2 (0.42) | NOS2NOS3NOS1MAPK1 | |
| SCHEMBL9427715 | 0.74 | NOS2 (0.47) | NOS2NOS3NOS1 | |
| SCHEMBL16228218 | 0.73 | NOS2 (0.58) | NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519996-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-12-30 | — | — | EP | disclosed |
| WO-1991013876-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |