Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954607 | 0.91 | CASR (0.36) | F10CASRADAM17MMP1KAT6A | |
| SCHEMBL9665265 | 0.89 | CASR (0.40) | F10CASRPLAUADAM17MMP1 | |
| SCHEMBL8954708 | 0.83 | CASR (0.39) | F10CASRPLAUADAM17MMP1 | |
| SCHEMBL8954993 | 0.81 | CASR (0.41) | F10CASRADAM17MMP1KAT6A | |
| SCHEMBL9665029 | 0.79 | CASR (0.41) | F10CASRPLAUKAT6AHCRTR1 | |
| SCHEMBL8954756 | 0.78 | F10 (0.38) | F10PLAUHCRTR1HCRTR2F2 | |
| SCHEMBL8954767 | 0.78 | F10 (0.50) | F10PLAUF2 | |
| Hydrochloric Acid SCHEMBL8954995 | 0.77 | F10 (0.49) | F10PLAUF2 | |
| SCHEMBL8954682 | 0.77 | ALOX5AP (0.38) | F10CASRADAM17MMP1KAT6A | |
| SCHEMBL9664400 | 0.76 | ALDH1A1 (0.47) | F10CASRPLAUKAT6AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |