Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954772 | 0.91 | F10 (0.40) | CASRF10KAT6AADAM17MMP1 | |
| SCHEMBL8954993 | 0.88 | CASR (0.41) | CASRF10KAT6AADAM17DPP4 | |
| SCHEMBL8954767 | 0.86 | F10 (0.50) | F10 | |
| Hydrochloric Acid SCHEMBL8954995 | 0.86 | F10 (0.49) | F10 | |
| SCHEMBL9665265 | 0.86 | CASR (0.40) | CASRF10KAT6AADAM17DPP4 | |
| SCHEMBL8954756 | 0.85 | F10 (0.38) | AKR1C3F10AKR1C1ACECAPN1 | |
| SCHEMBL8954843 | 0.82 | MMP8 (0.38) | CASRF10KAT6AACEPIN1 | |
| SCHEMBL8954682 | 0.82 | ALOX5AP (0.38) | CASRAKR1C3F10KAT6AADAM17 | |
| SCHEMBL9664400 | 0.79 | ALDH1A1 (0.47) | CASRF10KAT6ADPP7 | |
| SCHEMBL9665755 | 0.79 | CASR (0.38) | CASRF10KAT6AADAM17DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |