Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667096 | 0.90 | KMT2A (0.52) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9665330 | 0.89 | RAB9A (0.52) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9665290 | 0.88 | RAB9A (0.69) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9665730 | 0.88 | KMT2A (0.49) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9665257 | 0.88 | CYP2E1 (0.52) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9667102 | 0.87 | RAB9A (0.71) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9667456 | 0.87 | NPBWR1 (0.47) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9668116 | 0.86 | NPSR1 (0.54) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9665176 | 0.86 | RAB9A (0.44) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10684447 | 0.84 | RAB9A (0.43) | KMT2APOLBRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234980-B1 | 2-BENZIMIDAZOLYLALKYLTHIO (OR SULFINYL OR SULFONYL) DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-09-16 | — | — | EP | claimed |