Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.50 |
| ▸ | XBP1 | P17861 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5841555 | 0.88 | SMN1; SMN2 (0.50) | RAB9AHTTNPC1ALDH1A1MAPT | |
| SCHEMBL19000700 | 0.81 | RAB9A (0.61) | RAB9AHTTNPC1ALDH1A1MAPT | |
| SCHEMBL5843735 | 0.78 | HTT (0.45) | RAB9AHTTNPC1ALDH1A1MAPT | |
| SCHEMBL6955767 | 0.78 | ALDH1A1 (0.45) | RAB9AHTTNPC1ALDH1A1MAPT | |
| SCHEMBL4670658 | 0.78 | RAB9A (0.70) | RAB9AHTTNPC1ALDH1A1MAPT | |
| SCHEMBL13219469 | 0.76 | ALDH1A1 (0.54) | RAB9AHTTNPC1ALDH1A1MAPT | |
| SCHEMBL4672794 | 0.76 | RAB9A (0.69) | RAB9AHTTNPC1ALDH1A1MAPT | |
| SCHEMBL5842855 | 0.75 | RAB9A (0.40) | RAB9AHTTNPC1ALDH1A1MAPT | |
| SCHEMBL9666228 | 0.75 | MAPK14 (0.48) | MAPK14GAA | |
| SCHEMBL5841567 | 0.74 | RAB9A (0.42) | RAB9AHTTNPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210647-B1 | PYRIDAZINONE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND INSECTICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |
| EP-0210647-A2 | Pyridazinone derivatives, process for preparation thereof and insecticidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |