Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066637 | 0.85 | PLCG1 (0.53) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11150895 | 0.82 | RAB9A (0.47) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11148244 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11110585 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11160099 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11453132 | 0.79 | PLCG1 (0.41) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11116999 | 0.79 | PLCG1 (0.41) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11150066 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11147202 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDPLCG1TDP1 | |
| SCHEMBL11188743 | 0.77 | TDP1 (0.48) | ALDH1A1MAPTHPGDPLCG1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243686-B1 | BETA-LACTAM COMPOUNDS, AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |