Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11150895 | 0.86 | RAB9A (0.47) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL9666113 | 0.85 | ALDH1A1 (0.45) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11148244 | 0.84 | ALDH1A1 (0.44) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11110585 | 0.83 | ALDH1A1 (0.43) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11160099 | 0.83 | ALDH1A1 (0.43) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL9870975 | 0.82 | ALDH1A1 (0.49) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11147202 | 0.81 | ALDH1A1 (0.42) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11238305 | 0.81 | POLB (0.43) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11188743 | 0.81 | TDP1 (0.48) | PLCG1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL11173415 | 0.81 | ELANE (0.53) | PLCG1ALDH1A1MAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431587-A | AMINO ACID DERIVATIVE ANTIVBIOTICS | BEECHAM GROUP LIMITED (GB) | 1984-02-14 | — | — | US | disclosed |
| US-4405637-A | CARBAPENICILLIN | BEECHAM GROUP LIMITED (GB) | 1983-09-20 | — | — | US | disclosed |
| US-4401595-A | 4-Allyl azetidinone intermediate for β-lactam antibacterial agents | BEECHAM GROUP LIMITED (GB) | 1983-08-30 | — | — | US | disclosed |
| US-4350703-A | β-Lactam antibacterial agents | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |