Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9663956 | 0.86 | RAB9A (0.53) | MAPK14RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6370909 | 0.84 | MAPK14 (1.00) | MAPK14RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9666478 | 0.79 | RAB9A (0.48) | MAPK14RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9664607 | 0.78 | NPBWR1 (0.46) | MAPK14RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9664080 | 0.78 | NPBWR1 (0.46) | MAPK14RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10333020 | 0.77 | MAPK14 (0.44) | MAPK14RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6288420 | 0.76 | MAPK14 (1.00) | MAPK14ALDH1A1LMNAMEN1POLB | |
| SCHEMBL6234554 | 0.76 | MAPK14 (1.00) | MAPK14L3MBTL1ALDH1A1 | |
| SCHEMBL4675793 | 0.75 | RAB9A (0.71) | RAB9ASMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9372461 | 0.75 | MAPK14 (0.46) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210647-B1 | PYRIDAZINONE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND INSECTICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |
| US-4910201-A | With an ether substituted in position 5 | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0210647-A2 | Pyridazinone derivatives, process for preparation thereof and insecticidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |