Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 4/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664080 | 1.00 | NPBWR1 (0.46) | NPBWR1MAPK14ALDH1A1RAB9AMCHR1 | |
| SCHEMBL9663956 | 0.91 | RAB9A (0.53) | NPBWR1MAPK14ALDH1A1RAB9AMCHR1 | |
| SCHEMBL9666478 | 0.82 | RAB9A (0.48) | NPBWR1MAPK14ALDH1A1RAB9AMCHR1 | |
| SCHEMBL9283194 | 0.79 | NPC1 (0.52) | NPBWR1MAPK14ALDH1A1RAB9ASLC6A4 | |
| SCHEMBL9666271 | 0.78 | MAPK14 (0.72) | MAPK14ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9664510 | 0.77 | MAPK14 (0.43) | NPBWR1MAPK14ALDH1A1RAB9AMCHR1 | |
| SCHEMBL9663873 | 0.76 | MAPK14 (0.47) | MAPK14MAOAMAOBLMNASMN1; SMN2 | |
| SCHEMBL9663949 | 0.75 | ALDH1A1 (0.51) | NPBWR1MAPK14ALDH1A1RAB9AMCHR1 | |
| SCHEMBL4175570 | 0.75 | RAB9A (0.64) | NPBWR1ALDH1A1RAB9AMCHR1KMT2A | |
| SCHEMBL9666228 | 0.74 | MAPK14 (0.48) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210647-B1 | PYRIDAZINONE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND INSECTICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |
| US-4910201-A | With an ether substituted in position 5 | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0210647-A2 | Pyridazinone derivatives, process for preparation thereof and insecticidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |