Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 8/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPA3 | P15088 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668197 | 0.83 | HTT (0.46) | RAB9A | |
| SCHEMBL7141466 | 0.83 | CYP1A2 (0.67) | CPA1ANPEPERAP2ERAP1RAB9A | |
| SCHEMBL8716892 | 0.83 | RAB9A (0.61) | RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9668220 | 0.81 | RAB9A (0.49) | RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9668153 | 0.81 | RAB9A (0.46) | RAB9ANPC1 | |
| SCHEMBL7642680 | 0.80 | RAB9A (0.56) | RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9666561 | 0.80 | HTR2A (0.52) | RAB9A | |
| SCHEMBL11123380 | 0.79 | CPA1 (0.62) | CPA1ANPEPERAP2ERAP1CPB1 | |
| SCHEMBL10436410 | 0.78 | CPA1 (0.57) | CPA1ANPEPERAP2ERAP1RAB9A | |
| SCHEMBL7400156 | 0.78 | ITGA4 (0.55) | RAB9AITGA4ITGB7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219923-B1 | ANTIBIOTIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | claimed |
| EP-0219923-B1 | ANTIBIOTIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4956358-A | ANTIBIOTICS, BACTERICIDES, CEPHALOSPORINS AND ISOCEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4891427-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| US-4876251-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| US-4851422-A | Antibiotic 2-(3-oxo-2-isoxazolidinyl)-5-oxo-2-tetrahydrofuran-carboxylates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0253337-A2 | Tricyclic cepham compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |
| EP-0249909-A1 | Tricyclic penam compounds, their production and their use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| CN-86102923-A | The method for preparing antibiotic derivatives | — | 1986-11-12 | — | — | CN | disclosed |