Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531448 | 0.87 | DAGLA (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL29223593 | 0.80 | LMNA (0.33) | CPA1LMNAMEN1KMT2ATSHR | |
| SCHEMBL10531896 | 0.79 | LMNA (0.49) | ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL6341385 | 0.78 | ALDH1A1 (0.46) | CRHBPCRHR2CPA1ALDH1A1LMNA | |
| SCHEMBL9268412 | 0.77 | CRHBP (0.43) | CRHBPCRHR2CPA1ALDH1A1LMNA | |
| SCHEMBL29871382 | 0.76 | KMT2A (0.45) | CPA1ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL5097300 | 0.76 | CYP1A2 (0.41) | CPA1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9705115 | 0.74 | ALPI (0.46) | CPA1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12869897 | 0.74 | MEN1 (0.54) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9272378 | 0.72 | ESR1 (0.43) | CRHBPCRHR2CPA1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013965-A1 | METHOD OF IMMOBILIZING AND CROSSLINKING PROTEINS AND OTHER MOLECULES AND USES THEREOF | ANDERSON LESLIE DERIEMER (US) | 1992-08-20 | — | — | WO | disclosed |
| EP-0497585-A2 | Method of immobilizing and crosslinking proteins and other molecules and uses thereof | Anderson, Leslie Deriemer (US) | 1992-08-05 | — | — | EP | disclosed |