Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | USP19 | O94966 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669910 | 0.86 | KDM1A (0.47) | KMT2ATP53USP19TSHRHPGD | |
| Hydrochloric Acid SCHEMBL9669646 | 0.85 | KDM1A (0.46) | KMT2ATP53USP19TSHRHPGD | |
| SCHEMBL9668039 | 0.84 | TP53 (0.44) | TP53SMN1; SMN2ALDH1A1USP19TSHR | |
| SCHEMBL10405021 | 0.81 | HPGD (0.54) | MEN1KMT2ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9668346 | 0.81 | P2RX7 (0.45) | TP53SMN1; SMN2ALDH1A1USP19TSHR | |
| Cebaracetam SCHEMBL141165 | 0.78 | MDM2 (0.46) | TP53SMN1; SMN2USP19TSHRHPGD | |
| SCHEMBL9669356 | 0.78 | TP53 (0.54) | TP53SMN1; SMN2ALDH1A1TSHRHPGD | |
| Fumaric Acid SCHEMBL10405329 | 0.77 | DRD4 (0.49) | MEN1KMT2ATP53SMN1; SMN2ALDH1A1 | |
| Maleic Acid SCHEMBL9670470 | 0.77 | DRD4 (0.49) | MEN1KMT2ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL11239159 | 0.75 | TSHR (0.63) | MEN1KMT2AALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236263-B1 | SUBSTITUTED PYRROLIDINONES | CIBA-GEIGY AG (CH) | 1992-12-30 | — | — | EP | claimed |
| US-4945092-A | Substituted 1-(oxopyrrolidinylalkanoyl)-piperazines useful as nootropics | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | claimed |
| EP-0236263-A2 | Substituted pyrrolidinones | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | claimed |
| EP-0236263-B1 | SUBSTITUTED PYRROLIDINONES | CIBA-GEIGY AG (CH) | 1992-12-30 | — | — | EP | disclosed |
| US-4945092-A | Substituted 1-(oxopyrrolidinylalkanoyl)-piperazines useful as nootropics | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0236263-A2 | Substituted pyrrolidinones | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | disclosed |