Cebaracetam

Cebaracetam

SCHEMBL141165

O=C1CN(C(=O)CN2CC(c3ccc(Cl)cc3)CC2=O)CCN1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 10/20 0.46
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
TP53 P04637 3/20 0.41
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
USP19 O94966 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9668723 0.89 KDM1A (0.42) SMN1; SMN2L3MBTL1TP53TSHR
SCHEMBL9668039 0.86 TP53 (0.44) SMN1; SMN2TP53HPGDTSHRUSP19
SCHEMBL9668346 0.81 P2RX7 (0.45) MDM2SMN1; SMN2TP53HPGDTSHR
SCHEMBL9669910 0.80 KDM1A (0.47) TP53HPGDTSHRUSP19
Hydrochloric Acid SCHEMBL9669646 0.79 KDM1A (0.46) TP53HPGDTSHRUSP19
SCHEMBL9667995 0.78 MEN1 (0.46) SMN1; SMN2TP53GAARAB9AHPGD
SCHEMBL9669356 0.76 TP53 (0.54) MDM2SMN1; SMN2TP53HPGDTSHR
SCHEMBL10405021 0.75 HPGD (0.54) SMN1; SMN2TP53RAB9AHPGDTSHR
SCHEMBL9668508 0.75 MDM2 (0.42) MDM2TP53
SCHEMBL9668042 0.75 TP53 (0.57) SMN1; SMN2TP53HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
EP-0236263-B1 SUBSTITUTED PYRROLIDINONES CIBA-GEIGY AG (CH) 1992-12-30 EP claimed
US-4945092-A Substituted 1-(oxopyrrolidinylalkanoyl)-piperazines useful as nootropics CIBA-GEIGY CORPORATION (US) 1990-07-31 US claimed
EP-0236263-A2 Substituted pyrrolidinones CIBA-GEIGY AG (CH) 1987-09-09 EP claimed
US-20260124244-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES STELLULAR BIO, INC. (US) 2026-05-07 US disclosed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
WO-1997044063-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES NEUROMEDICA, INC. (US) 1997-11-27 WO disclosed
EP-0236263-B1 SUBSTITUTED PYRROLIDINONES CIBA-GEIGY AG (CH) 1992-12-30 EP disclosed
US-4945092-A Substituted 1-(oxopyrrolidinylalkanoyl)-piperazines useful as nootropics CIBA-GEIGY CORPORATION (US) 1990-07-31 US disclosed
EP-0236263-A2 Substituted pyrrolidinones CIBA-GEIGY AG (CH) 1987-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A MDM2 2377/4885SMN1; SMN2 101/4885L3MBTL1 3941/4885
US-20260124244-A1 MEGAKARYOCYTE DERIVATIVES FOR TREATMENT OF DRY EYE DISEASES MYH10, PDGFA, MPL MDM2 2858/4885SMN1; SMN2 1472/4885L3MBTL1 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.