Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928222 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HTTHRH3SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9851658 | 0.76 | ALDH1A1 (0.70) | ALDH1A1HTTHRH3SLC6A4SLC6A3 | |
| SCHEMBL9381303 | 0.76 | ALDH1A1 (0.69) | ALDH1A1HTTHRH3POLBSLC6A4 | |
| SCHEMBL15503835 | 0.74 | ALDH1A1 (0.97) | ALDH1A1HTTHRH3POLBLMNA | |
| SCHEMBL9667209 | 0.73 | CYP2D6 (0.67) | ALDH1A1HTTLMNAHIF1ASLC6A4 | |
| SCHEMBL678935 | 0.73 | KMT2A (0.57) | ALDH1A1HTTPOLBMITFSMN1; SMN2 | |
| SCHEMBL2516637 | 0.72 | L3MBTL1 (0.59) | ALDH1A1POLBSMN1; SMN2LMNAKMT2A | |
| SCHEMBL15935698 | 0.72 | ALDH1A1 (0.94) | ALDH1A1HTTHRH3POLBLMNA | |
| SCHEMBL10911370 | 0.71 | L3MBTL1 (0.58) | ALDH1A1POLBSMN1; SMN2LMNAKMT2A | |
| SCHEMBL1550630 | 0.71 | L3MBTL1 (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506903-A1 | 4-ACETOXY-PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE AS A MUSCARINIC M3-RECEPTOR ANTAGONIST | BTG INTERNATIONAL LIMITED (GB) | 1992-10-07 | — | — | EP | disclosed |
| WO-1992006958-A1 | 4-ACETOXY-PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE AS A MUSCARINIC M3-RECEPTOR ANTAGONIST | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-04-30 | — | — | WO | disclosed |