Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016911 | 0.87 | L3MBTL1 (0.55) | HTTKMT2AMEN1MCOLN3ACHE | |
| SCHEMBL3788597 | 0.85 | HTT (0.56) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL29039328 | 0.80 | HTR2A (0.63) | HTTKMT2AMEN1ACHELMNA | |
| SCHEMBL30385718 | 0.80 | HTR2A (0.63) | HTTKMT2AMEN1ACHELMNA | |
| SCHEMBL3793071 | 0.76 | KMT2A (0.55) | HTTKMT2AMEN1LMNA | |
| SCHEMBL16429902 | 0.75 | KMT2A (0.64) | KMT2AMEN1MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL12856209 | 0.74 | POLB (0.50) | POLBKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL23310509 | 0.74 | KMT2A (0.58) | POLBKMT2AMEN1LMNAMAPT | |
| SCHEMBL16485862 | 0.74 | L3MBTL1 (0.51) | POLBKMT2AMEN1ACHEL3MBTL1 | |
| SCHEMBL9491484 | 0.73 | MTNR1A (0.63) | KMT2AMEN1MTNR1AMTNR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509005-A1 | DIPHENYLSULPHOXIMINE MUSCARINIC RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1992-10-21 | — | — | EP | disclosed |