Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645137 | 0.79 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL31667227 | 0.77 | MEN1 (0.61) | ALOX5 | |
| SCHEMBL9645952 | 0.74 | ALOX5 (0.70) | ALOX5 | |
| SCHEMBL9645961 | 0.72 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL9596545 | 0.71 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9646598 | 0.71 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9646928 | 0.71 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9646860 | 0.70 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9647813 | 0.69 | ADAM17 (0.55) | ALOX5 | |
| SCHEMBL1069838 | 0.69 | ALOX5 (0.59) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | claimed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | claimed |