Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440607 | 0.90 | LMNA (0.49) | HTTKMT2AGAAHPGDMEN1 | |
| SCHEMBL27205433 | 0.90 | ALDH1A1 (0.54) | HTTKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL8578095 | 0.87 | AKR1C3 (0.55) | HTTKMT2AGAAHPGDMEN1 | |
| SCHEMBL17557422 | 0.85 | HTT (0.44) | HTTKMT2AGAAHPGDMEN1 | |
| SCHEMBL3440477 | 0.85 | TSHR (0.63) | KMT2AHPGDMEN1ALDH1A1MAPT | |
| SCHEMBL709788 | 0.84 | POLB (0.68) | HTTKMT2AGAAHPGDMEN1 | |
| SCHEMBL26622207 | 0.84 | HTT (0.53) | HTTKMT2AGAAHPGDMEN1 | |
| SCHEMBL29391544 | 0.84 | POLB (0.68) | HTTKMT2AGAAHPGDMEN1 | |
| SCHEMBL2199723 | 0.84 | ALDH1A1 (0.58) | HTTKMT2AGAAHPGDMEN1 | |
| SCHEMBL11757707 | 0.82 | PLK1 (0.50) | HTTKMT2AGAAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107278205-A | Substituted nucleoside derivates as anticarcinogen | 辉瑞大药厂 | 2017-10-20 | — | — | CN | disclosed |
| EP-0508999-A1 | PHARMACEUTICALLY ACTIVE NORMONYL COMPOUNDS | Beecham Group p.l.c. (GB) | 1992-10-21 | — | — | EP | disclosed |