SCHEMBL9669448

SCHEMBL9669448

O=C1[CH]NC(=O)c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.52
MAOA P21397 4/20 0.48
MAOB P27338 3/20 0.48
CDC25B P30305 3/20 0.48
IDO1 P14902 2/20 0.48
SNCA P37840 2/20 0.48
AKT1 P31749 1/20 0.48
MAP2K1 Q02750 1/20 0.48
PIN1 Q13526 1/20 0.48
EHMT2 Q96KQ7 1/20 0.48
NSD1 Q96L73 1/20 0.48
EHMT1 Q9H9B1 1/20 0.48
CASP3 P42574 1/20 0.44
CASP2 P42575 1/20 0.44
CASP7 P55210 1/20 0.44
CASP6 P55212 1/20 0.44
CASP8 Q14790 1/20 0.44
PDGFRA P16234 1/20 0.43
FER P16591 1/20 0.43
LTK P29376 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19471848 0.75 GSK3B (0.46) GSK3BMAOAMAOBCDC25BIDO1
Phthalimide SCHEMBL9229 0.73 GSK3B (0.94) GSK3BMAOAMAOBCDC25BCASP3
Phthalimide SCHEMBL1205291 0.73 GSK3B (0.94) GSK3BMAOAMAOBCDC25BCASP3
SCHEMBL3626475 0.71
Phthalimide SCHEMBL10592849 0.70 GSK3B (0.88) GSK3BMAOAMAOBCDC25BCASP3
Naphthoquinone SCHEMBL10949679 0.70 GSK3B (0.75) GSK3BMAOAMAOBCDC25BIDO1
Phthalimide SCHEMBL11040503 0.69 GSK3B (1.00) GSK3BMAOAMAOBCDC25BEHMT2
Phthalimide SCHEMBL30125197 0.69 GSK3B (1.00) GSK3BMAOAMAOBCDC25BEHMT2
Phthalimide SCHEMBL64 0.69 GSK3B (1.00) GSK3BMAOAMAOBCDC25BEHMT2
Phthalimide SCHEMBL29366030 0.69 GSK3B (1.00) GSK3BMAOAMAOBCDC25BEHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114791694-A External additive for toner and toner 佳能株式会社 2022-07-26 CN disclosed
EP-0237027-B1 6-(DISUBSTITUTED AMINO) CARBAPENAM COMPOUNDS Sanraku Incorporated (JP) 1992-06-10 EP disclosed
US-4996314-A 6-(disubstituted amino)carbapenem compounds SANRAKU INCORPORATED (JP) 1991-02-26 US disclosed
US-4812563-A ANTIBIOTICS SANRAKU INCORPORATED (JP) 1989-03-14 US disclosed
EP-0237027-A2 6-(Disubstituted amino) carbapenam compounds Sanraku Incorporated (JP) 1987-09-16 EP disclosed
EP-0105227-A1 Process for producing beta-lactam compounds, and intermediates useful for their production Sanraku Incorporated (JP) 1984-04-11 EP disclosed
EP-0040408-A1 Beta-lactam compounds and process for production thereof SANRAKU-OCEAN CO., LTD. (JP) 1981-11-25 EP disclosed