Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA6 | P23280 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1891641 | 0.82 | SENP2 (0.58) | LDHAALDH1A1SUMO2SUMO1SENP7 | |
| SCHEMBL10605483 | 0.82 | LDHA (0.58) | CA2CA1CA4CA9CA6 | |
| SCHEMBL31222829 | 0.82 | SENP2 (0.58) | LDHAALDH1A1SUMO2SUMO1SENP7 | |
| SCHEMBL4456435 | 0.81 | SENP2 (0.56) | LDHAALDH1A1SUMO2SUMO1SENP7 | |
| SCHEMBL9669785 | 0.78 | CDK2 (0.58) | CA2CA1CA4CA9CA6 | |
| Hydrochloric Acid SCHEMBL9670851 | 0.77 | CDK2 (0.56) | CA2CA1CA4CA9CA6 | |
| SCHEMBL108422 | 0.75 | LDHA (0.64) | CA2CA1CA4CA9CA6 | |
| SCHEMBL3149871 | 0.73 | CA1 (0.59) | CA2CA1CA4CA9CA6 | |
| SCHEMBL7535265 | 0.72 | MCL1 (0.67) | CA2CA1CA9CYP2C9LDHA | |
| SCHEMBL23787622 | 0.71 | APP (0.78) | HSD17B10ALDH1A1SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283959-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-02 | — | — | EP | disclosed |
| US-4912108-A | Containing hydroxy substitution | A/S FERROSAN (DK) | 1990-03-27 | — | — | US | disclosed |
| US-4889855-A | ADMINISTERING GLUTAMATE ANTAGONIST TO INHIBIT HYPERACTIVITY OF EXCITATORY NEUROTRANSMITTERS | A/S FERROSAN (DK) | 1989-12-26 | — | — | US | disclosed |
| EP-0283959-A1 | Heterocyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-09-28 | — | — | EP | disclosed |