Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670215 | 1.00 | CTSK (0.44) | CTSKPOLBMMP2MMP3CTSV | |
| SCHEMBL9745321 | 0.85 | HDAC8 (0.40) | — | |
| SCHEMBL9326292 | 0.83 | POLB (0.51) | POLBMMP2MMP3 | |
| SCHEMBL8985048 | 0.83 | POLB (0.51) | POLBMMP2MMP3 | |
| SCHEMBL9672430 | 0.82 | NAAA (0.40) | — | |
| Benzene SCHEMBL9328037 | 0.81 | PDCD4 (0.45) | — | |
| SCHEMBL9422785 | 0.80 | CTSK (0.45) | CTSKPOLBMMP2MMP3CTSV | |
| SCHEMBL9422783 | 0.80 | CTSK (0.45) | CTSKPOLBMMP2MMP3CTSV | |
| SCHEMBL9328030 | 0.80 | TSHR (0.41) | — | |
| SCHEMBL9671381 | 0.79 | PDCD4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |