Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670375 | 0.85 | CTSK (0.44) | — | |
| SCHEMBL9670215 | 0.85 | CTSK (0.44) | — | |
| SCHEMBL9672430 | 0.85 | NAAA (0.40) | EPHX1 | |
| Benzene SCHEMBL9328037 | 0.83 | PDCD4 (0.45) | ALDH1A1 | |
| SCHEMBL9328030 | 0.82 | TSHR (0.41) | ALDH1A1KMT2A | |
| SCHEMBL8985056 | 0.82 | HDAC8 (0.45) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL8657153 | 0.81 | HDAC8 (0.40) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL14339054 | 0.81 | PDCD4 (0.47) | — | |
| SCHEMBL7294590 | 0.81 | PDCD4 (0.47) | — | |
| SCHEMBL9671381 | 0.81 | PDCD4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |