Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985077 | 0.94 | NAAA (0.43) | FAAHNAAA | |
| SCHEMBL9670637 | 0.94 | NAAA (0.43) | FAAHNAAA | |
| SCHEMBL9671073 | 0.94 | NAAA (0.43) | FAAHNAAA | |
| SCHEMBL9669974 | 0.89 | NAAA (0.40) | MMP12FAAHNAAA | |
| SCHEMBL9671365 | 0.89 | RARB (0.40) | NAAA | |
| SCHEMBL8985071 | 0.86 | HDAC1 (0.40) | NAAAHDAC1 | |
| SCHEMBL9735619 | 0.84 | NAAA (0.35) | NAAA | |
| SCHEMBL9735612 | 0.84 | NAAA (0.35) | NAAA | |
| SCHEMBL9671190 | 0.84 | ALOX5 (0.36) | — | |
| Benzene SCHEMBL9328037 | 0.82 | PDCD4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |