Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGFR | P43088 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735612 | 1.00 | NAAA (0.35) | NAAAPTGER3PTGER1PTGER4PTGFR | |
| SCHEMBL9670637 | 0.90 | NAAA (0.43) | NAAA | |
| SCHEMBL8985077 | 0.90 | NAAA (0.43) | NAAA | |
| SCHEMBL9671073 | 0.90 | NAAA (0.43) | NAAA | |
| SCHEMBL9669974 | 0.88 | NAAA (0.40) | NAAA | |
| SCHEMBL9670400 | 0.84 | MMP12 (0.45) | NAAA | |
| SCHEMBL9671190 | 0.82 | ALOX5 (0.36) | KDM4EMEN1KMT2A | |
| Benzene SCHEMBL9328037 | 0.81 | PDCD4 (0.45) | — | |
| SCHEMBL9671365 | 0.81 | RARB (0.40) | NAAAPTGER3PTGER4MEN1MAPT | |
| SCHEMBL9670188 | 0.79 | PDCD4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |