Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 1/20 | 0.54 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102975 | 0.92 | LYPLA1 (0.49) | LYPLA1LYPLA2HRH3KEAP1NFE2L2 | |
| SCHEMBL8352890 | 0.89 | LYPLA1 (0.58) | LYPLA1LYPLA2LTA4HUSP2TAAR1 | |
| SCHEMBL881823 | 0.88 | ALDH1A1 (0.54) | LYPLA1LYPLA2HRH3KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL30678583 | 0.87 | LYPLA1 (0.57) | LYPLA1LYPLA2LTA4HUSP2TAAR1 | |
| SCHEMBL3114914 | 0.86 | LYPLA1 (0.44) | LYPLA1LYPLA2HRH3KEAP1NFE2L2 | |
| SCHEMBL24942155 | 0.85 | HRH3 (0.47) | LYPLA1LYPLA2HRH3KEAP1NFE2L2 | |
| SCHEMBL188151 | 0.85 | LYPLA1 (0.44) | LYPLA1LYPLA2HRH3KEAP1NFE2L2 | |
| SCHEMBL3146045 | 0.85 | HRH3 (0.46) | LYPLA1LYPLA2HRH3LMNACHRM2 | |
| SCHEMBL8133937 | 0.84 | ALDH1A1 (0.53) | LYPLA1LYPLA2ALDH1A1 | |
| SCHEMBL4757062 | 0.82 | LYPLA1 (0.42) | LYPLA1LYPLA2HRH3KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |
| US-4323454-A | CURED EPOXY RESIN, FILLER, HOLLOW FIBERS | MONSANTO COMPANY (US) | 1982-04-06 | — | — | US | disclosed |
| US-4323453-A | EPOXY RESIN CURED WITH AN IMIDAZOLE, HOLLOW FIBERS | MONSANTO COMPANY (US) | 1982-04-06 | — | — | US | disclosed |
| US-4090988-A | Polyurethane foam preparation using pyridine ether catalysts | OLIN CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |