SCHEMBL3146045

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9670428	0.85	LYPLA1 (0.54)	HRH3KCNH2LYPLA1LYPLA2ADRA2A
	SCHEMBL8897670	0.81	ALDH1A1 (0.54)	THRATHRBESR1ADRA2AADORA3
	SCHEMBL874146	0.79	HRH3 (0.74)	HRH3KCNH2ESR1KDM4EALDH1A1
	SCHEMBL3053110	0.79	HRH3 (0.64)	HRH3KCNH2THRATHRBALDH1A1
	SCHEMBL13102975	0.78	LYPLA1 (0.49)	HRH3KCNH2LYPLA1LYPLA2KDM4E
	SCHEMBL2093823	0.77	ALDH1A1 (0.51)	THRATHRBESR1ADRA2AADORA3
	SCHEMBL20691211	0.77	L3MBTL1 (0.58)	KCNH2TDP1L3MBTL1ESR1ADRA2A
	SCHEMBL8352890	0.76	LYPLA1 (0.58)	KCNH2LYPLA1LYPLA2ADRA2ASLC6A2
	SCHEMBL12051786	0.75	ALDH1A1 (0.70)	HRH3THRATHRBKDM4EALDH1A1
	SCHEMBL9598141	0.75	ALDH1A1 (0.63)	HRH3THRBESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.