Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671948 | 0.94 | ALDH1A1 (0.51) | ARPELP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL25484968 | 0.86 | ALDH1A1 (0.50) | ARPELP1NPC1RAB9AALDH1A1 | |
| SCHEMBL11247732 | 0.83 | CASP6 (0.57) | NPC1RAB9AALDH1A1KMT2AVCAM1 | |
| SCHEMBL7549466 | 0.83 | PDK1 (0.51) | ARPELP1ALDH1A1HTTMYC | |
| SCHEMBL23628904 | 0.82 | AR (0.50) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1497352 | 0.81 | AR (0.49) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1346767 | 0.81 | AR (0.61) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL25484985 | 0.81 | PDE5A (0.43) | ARPELP1ALDH1A1KMT2ALMNA | |
| SCHEMBL31615843 | 0.80 | KDM4E (0.61) | PRSS1ALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL1027488 | 0.80 | TSHR (0.62) | NPC1RAB9AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141627-A | Calcium concentration of blood | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-08-25 | — | — | US | disclosed |