Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672149 | 0.89 | CYP3A4 (0.36) | NPY5RADRB3SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL9672246 | 0.88 | ALDH1A1 (0.38) | ADRB3SMN1; SMN2NOTUMALDH1A1TSHR | |
| SCHEMBL9672110 | 0.83 | LMNA (0.37) | NPY5RSMN1; SMN2NOTUMALDH1A1TSHR | |
| SCHEMBL9672365 | 0.81 | GLB1 (0.43) | HDAC6 | |
| SCHEMBL9671642 | 0.80 | NOTUM (0.37) | SMN1; SMN2NOTUMALDH1A1TSHRCYP3A4 | |
| SCHEMBL9670596 | 0.74 | CYP3A4 (0.37) | NPY5RSMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL9800240 | 0.73 | CYP11B2 (0.40) | SMN1; SMN2NOTUMALDH1A1TSHRCYP3A4 | |
| SCHEMBL9673220 | 0.73 | LMNA (0.36) | NPY5RSMN1; SMN2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL9217487 | 0.67 | NPY5R (0.34) | NPY5RSMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL9212001 | 0.67 | NPY5R (0.34) | NPY5RSMN1; SMN2ALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-A1 | THIOFORMAMIDE DERIVATIVES. | RHONE POULENC RORER SA (FR) | 1992-10-28 | — | — | EP | disclosed |