SCHEMBL9670752

SCHEMBL9670752

Cc1ccc(CC(=O)N2CCCC3CCCC(N4CCCC4)C32)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 15/20 0.53
OPRM1 P35372 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9672121 0.88 OPRK1 (0.50) OPRK1OPRM1
SCHEMBL9672126 0.88 OPRK1 (0.50) OPRK1OPRM1
SCHEMBL9672636 0.88 OPRK1 (0.56) OPRK1OPRM1
SCHEMBL9670691 0.85 OPRK1 (0.47) OPRK1OPRM1
SCHEMBL9670929 0.85 OPRD1 (0.57) OPRK1OPRM1
SCHEMBL9670754 0.85 OPRD1 (0.57) OPRK1OPRM1
SCHEMBL9669600 0.82 OPRK1 (0.73) OPRK1OPRM1
SCHEMBL9669595 0.82 OPRK1 (0.73) OPRK1OPRM1
SCHEMBL9788886 0.82 OPRK1 (0.73) OPRK1OPRM1
SCHEMBL9672001 0.81 OPRK1 (0.72) OPRK1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0233793-B1 DECAHYDROQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1992-04-01 EP disclosed