Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670929 | 1.00 | OPRD1 (0.57) | OPRD1OPRK1OPRM1 | |
| SCHEMBL9670691 | 0.85 | OPRK1 (0.47) | OPRK1OPRM1 | |
| SCHEMBL9672126 | 0.85 | OPRK1 (0.50) | OPRK1OPRM1 | |
| SCHEMBL9672121 | 0.85 | OPRK1 (0.50) | OPRK1OPRM1 | |
| SCHEMBL9670752 | 0.85 | OPRK1 (0.53) | OPRK1OPRM1 | |
| SCHEMBL9672636 | 0.84 | OPRK1 (0.56) | OPRK1OPRM1 | |
| SCHEMBL9670936 | 0.81 | OPRD1 (0.54) | OPRD1 | |
| SCHEMBL9788886 | 0.80 | OPRK1 (0.73) | OPRK1OPRM1 | |
| SCHEMBL9669595 | 0.80 | OPRK1 (0.73) | OPRK1OPRM1 | |
| SCHEMBL9669600 | 0.80 | OPRK1 (0.73) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233793-B1 | DECAHYDROQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-04-01 | — | — | EP | claimed |