Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.45 |
| ▸ | MAOB | P27338 | 9/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672219 | 0.95 | MAOA (0.46) | MAOAMAOBPRKCIMEN1MAPK1 | |
| SCHEMBL6952322 | 0.80 | CYP2A6 (0.41) | MAOANPSR1CYP2A6CYP3A4HSD17B10 | |
| SCHEMBL10334537 | 0.78 | CYP2A6 (0.40) | MAOANPSR1CYP2A6CYP3A4HSD17B10 | |
| SCHEMBL9671166 | 0.76 | HPGD (0.42) | MAOAMEN1MAPK1KMT2ACYP2A6 | |
| SCHEMBL6947277 | 0.76 | CYP2A6 (0.41) | MAOANPSR1CYP2A6CYP3A4HSD17B10 | |
| SCHEMBL26724412 | 0.74 | CYP2A6 (0.48) | MAOAMAOBCYP2A6CYP3A4HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL8845141 | 0.74 | CYP2A6 (0.40) | MAOANPSR1CYP2A6CYP3A4HSD17B10 | |
| SCHEMBL7586133 | 0.73 | MAOA (0.59) | MAOAMAOBPRKCIMEN1MAPK1 | |
| SCHEMBL6052782 | 0.73 | CYP2A6 (0.47) | MAOACYP2A6CYP3A4HSD17B10KDM4E | |
| SCHEMBL31643666 | 0.73 | MAOA (0.59) | MAOAMAOBPRKCIMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286516-B1 | Amino-5,6,7,8-tetrahydro-naphtho[2,3b]furan derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-03-18 | — | — | EP | claimed |
| WO-2021183980-A1 | SUBSTITUTED PYRIMIDINES AND TRIAZINES AS HERBICIDES | FMC CORPORATION (US) | 2021-09-16 | — | — | WO | disclosed |