Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025208 | 0.85 | POLB (0.68) | ALDH1A1POLBKDM4ESMN1; SMN2GAA | |
| SCHEMBL10914671 | 0.84 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1POLBCYP2C19 | |
| SCHEMBL16134867 | 0.83 | POLB (0.70) | KMT2AALDH1A1POLBCYP2C19KDM4E | |
| SCHEMBL9513235 | 0.83 | KMT2A (0.67) | KMT2AMEN1ALDH1A1POLBCYP2C19 | |
| SCHEMBL10915286 | 0.83 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1POLBCYP2C19 | |
| SCHEMBL31178415 | 0.83 | KMT2A (0.83) | KMT2AMEN1ALDH1A1POLBCYP2C19 | |
| SCHEMBL9512949 | 0.83 | KMT2A (0.83) | KMT2AMEN1ALDH1A1POLBCYP2C19 | |
| SCHEMBL10977359 | 0.82 | DRD2 (0.73) | DRD3HPGD | |
| SCHEMBL25732912 | 0.82 | KDM4E (0.80) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL31326927 | 0.82 | KDM4E (0.80) | KMT2AMEN1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254322-B1 | BENZIMIDAZOLE DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4886803-A | CARDIOTONIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0254322-A1 | Benzimidazole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |
| EP-0040793-B1 | NOVEL QUINAZOLINE-DIONE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL USE THEREOF | Ishikawa, Masayuki (JP) | 1985-08-28 | — | — | EP | disclosed |
| US-4405623-A | HYPOTENSIVE AGENTS, VASODILATORS | MASAYUKI ISHIKAWA (JP) | 1983-09-20 | — | — | US | disclosed |
| EP-0040793-A1 | Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof | Ishikawa, Masayuki (JP) | 1981-12-02 | — | — | EP | disclosed |