Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914671 | 0.88 | ALDH1A1 (0.64) | ALDH1A1POLBCYP2C19KDM4EGAA | |
| SCHEMBL31326927 | 0.83 | KDM4E (0.80) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL25732912 | 0.83 | KDM4E (0.80) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL9671229 | 0.83 | KMT2A (0.70) | ALDH1A1POLBCYP2C19KDM4EGAA | |
| SCHEMBL10826186 | 0.82 | DRD2 (0.67) | ALDH1A1GAAKMT2AMEN1HPGD | |
| Hydrochloric Acid SCHEMBL10911419 | 0.81 | KMT2A (0.69) | ALDH1A1POLBCYP2C19KDM4EGAA | |
| SCHEMBL16134867 | 0.81 | POLB (0.70) | ALDH1A1POLBCYP2C19KDM4EGAA | |
| SCHEMBL31178415 | 0.81 | KMT2A (0.83) | ALDH1A1POLBCYP2C19KDM4EGAA | |
| SCHEMBL9512949 | 0.81 | KMT2A (0.83) | ALDH1A1POLBCYP2C19KDM4EGAA | |
| SCHEMBL10913783 | 0.80 | KMT2A (0.71) | ALDH1A1POLBCYP2C19KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585774-A | Aniline derivatives and cardiotonic composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0064878-B1 | NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0064878-A1 | Novel aniline derivatives, process for preparing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-11-17 | — | — | EP | disclosed |