SCHEMBL9673159

SCHEMBL9673159

O=C1c2cnccc2-c2ncccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.66
MAOB P27338 1/20 0.66
GAA P10253 1/20 0.64
PTPRC P08575 2/20 0.63
CTSL P07711 1/20 0.63
CTSS P25774 1/20 0.63
PTPN13 Q12923 1/20 0.63
TDP2 O95551 3/20 0.59
NSD2 O96028 3/20 0.59
PAX8 Q06710 3/20 0.59
ABL1 P00519 1/20 0.59
PLCG1 P19174 1/20 0.59
CES1 P23141 1/20 0.59
RIN1 Q13671 1/20 0.59
TDP1 Q9NUW8 2/20 0.53
MEN1 O00255 1/20 0.53
THRB P10828 1/20 0.53
BLM P54132 1/20 0.53
KMT2A Q03164 1/20 0.53
S100A4 P26447 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556066 0.96 PTPRC (0.69) MAOAMAOBGAAPTPRCCTSL
SCHEMBL9672513 0.93 MAOA (0.66) MAOAMAOBGAAPTPRCCTSL
SCHEMBL16352242 0.91 MAOA (0.69) MAOAMAOBGAAPTPRCCTSL
SCHEMBL28663543 0.89 MAOA (0.72) MAOAMAOBGAAPTPRCCTSL
SCHEMBL30799541 0.82 PTPRC (0.91) MAOAGAAPTPRCCTSLCTSS
SCHEMBL69772 0.82 PTPRC (0.91) MAOAGAAPTPRCCTSLCTSS
SCHEMBL29350676 0.80 MAOA (1.00) MAOAMAOBGAAPTPRCCTSL
SCHEMBL421291 0.80 MAOA (1.00) MAOAMAOBGAAPTPRCCTSL
SCHEMBL30774319 0.80 GAA (1.00) GAAPTPRCCTSLCTSSPTPN13
SCHEMBL29551149 0.80 GAA (1.00) GAAPTPRCCTSLCTSSPTPN13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513014-B Light stabilizer compounds, compositions and methods ELC 管理有限责任公司 2024-01-30 CN disclosed
US-11655215-B2 Photostabilizing compounds, compositions, and methods ELC MANAGEMENT LLC (US) 2023-05-23 US disclosed
US-11655215-B2 Photostabilizing compounds, compositions, and methods ELC MANAGEMENT LLC (US) 2023-05-23 US disclosed
US-11655215-B2 Photostabilizing compounds, compositions, and methods ELC MANAGEMENT LLC (US) 2023-05-23 US disclosed
US-20210163419-A1 PHOTOSTABILIZING COMPOUNDS, COMPOSITIONS, AND METHODS ELC MAN LLC (US) 2021-06-03 US disclosed
US-20210163419-A1 PHOTOSTABILIZING COMPOUNDS, COMPOSITIONS, AND METHODS ELC MAN LLC (US) 2021-06-03 US disclosed
EP-3807247-A1 PHOTOSTABILIZING COMPOUNDS, COMPOSITIONS, AND METHODS ELC Management LLC (US) 2021-04-21 EP disclosed
CN-112513014-A Light stabilizer compounds, compositions and methods ELC 管理有限责任公司 2021-03-16 CN disclosed
WO-2016086071-A1 SPECTRALLY ENCODED CONSUMABLE SPECTROMETER APPARATUS AND METHODS NUEOU, INC. (US) 2016-06-02 WO disclosed
US-5153211-A Enzyme inhibitors ALCON LABORATORIES, INC. (US) 1992-10-06 US disclosed
US-5070100-A COMPLICATIONS OF DIABETES ALCON LABORATORIES, INC. (US) 1991-12-03 US disclosed
US-4864028-A ANTIDIABETIC AGENTS ALCON LABORATORIES, INC. (US) 1989-09-05 US disclosed
US-4537892-A ANTIDIABETIC AGENTS ALCON LABORATORIES, INC. (US) 1985-08-27 US disclosed
EP-0137333-A2 Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase ALCON LABORATORIES, INC. (US) 1985-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163419-A1 PHOTOSTABILIZING COMPOUNDS, COMPOSITIONS, AND METHODS TYR, NISCH, PPOX MAOA 109/4885MAOB 130/4885GAA 2295/4885
US-11655215-B2 Photostabilizing compounds, compositions, and methods TYR, NISCH, PPOX MAOA 109/4885MAOB 130/4885GAA 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.