Sugi Predict

Sugi Predict / Compounds / SCHEMBL421291

SCHEMBL421291

SCHEMBL421291

O=C1c2ccccc2C(=O)c2cnccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 2/20 1.00
▸ MAOB P27338 1/20 1.00
▸ CDC25B P30305 2/20 0.65
▸ MEN1 O00255 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ MAPT P10636 5/20 0.52
▸ SMN1; SMN2 Q16637 5/20 0.52
▸ BLM P54132 4/20 0.52
▸ TP53 P04637 4/20 0.52
▸ CYP3A4 P08684 4/20 0.52
▸ CASP1 P29466 3/20 0.52
▸ MAPK1 P28482 2/20 0.52
▸ TSHR P16473 2/20 0.52
▸ CASP7 P55210 2/20 0.52
▸ KDM4E B2RXH2 2/20 0.50
▸ NPC1 O15118 2/20 0.48
▸ RAB9A P51151 2/20 0.48
▸ PTPRC P08575 2/20 0.48
▸ HTT P42858 2/20 0.48
▸ APAF1 O14727 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350676 1.00 MAOA (1.00) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL6926901 0.98 MAOA (0.95) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL3066734 0.93 MAOA (0.87) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL19013209 0.93 MAOA (0.87) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL8417659 0.93 MAOA (0.86) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL30616365 0.93 MAOA (0.86) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL9269089 0.87 MAOA (0.77) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL20618218 0.87 MAOA (0.77) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL31112247 0.87 MAOA (0.77) MAOAMAOBCDC25BMEN1KMT2A
SCHEMBL13072293 0.86 MAOA (0.74) MAOAMAOBCDC25BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260097359-A1 MULTI-TUBULAR ELECTROCHEMICAL CELL FOR TARGET SPECIES SEPARATIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-04-09 — — US disclosed
US-12458922-B2 Electroactive species and method for electrochemical gas separation VERDOX, INC. (US) 2025-11-04 — — US disclosed
US-20250312733-A1 METHOD FOR ELECTROCHEMICAL GAS SEPARATION VERDOX INC (US) 2025-10-09 — — US disclosed
US-12364949-B2 Method for electrochemical gas separation VERDOX, INC. (US) 2025-07-22 — — US disclosed
CN-114599443-B Electrochemical capture of lewis acid gases 麻省理工学院 2024-10-25 — — CN disclosed
US-20240173668-A1 METHOD FOR ELECTROCHEMICAL GAS SEPARATION VERDOX, INC 2024-05-30 — — US disclosed
EP-4363083-A1 ELECTROACTIVE SPECIES AND METHOD FOR ELECTROCHEMICAL GAS SEPARATION Verdox, Inc. (US) 2024-05-08 — — EP disclosed
US-20240139675-A1 ELECTROCHEMICAL CAPTURE OF LEWIS ACID GASES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-05-02 — — US disclosed
WO-2024064256-A1 MULTI-TUBULAR ELECTROCHEMICAL CELL FOR TARGET SPECIES SEPARATIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-03-28 — — WO disclosed
US-11931692-B2 Method for electrochemical gas separation VERDOX, INC (US) 2024-03-19 — — US disclosed
US-20050222190-A1 1,4-bis-N-oxide azaanthracenediones and the use thereof CURD JOHN G 2005-10-06 — — US disclosed
EP-1001936-A1 BIS -ACRIDINECARBOXAMIDE HAVING ANTI-TUMOR ACTIVITY Universita degli Studi di Camerino (IT) 2000-05-24 — — EP disclosed
WO-1999006372-A1 BIS-ACRIDINECARBOXAMIDES HAVING ANTITUMOR ACTIVITY UNIVERSITA' DEGLI STUDI DI CAMERINO (IT) 1999-02-11 — — WO disclosed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS — 1998-12-30 — — WO disclosed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 — — WO disclosed
US-5616709-A Method of synthesis for 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and its dimaleate salt BOEHRINGER MANNHEIM GMBH (IT) 1997-04-01 — — US disclosed
EP-0752857-A1 AN IMPROVED METHOD OF SYNTHESIS FOR 6,9-BIS (2-AMINOETHYL)AMINO]BENZO g]ISOQUINOLINE-5,10-DIONE AND ITS DIMALEATE SALT BOEHRINGER MANNHEIM ITALIA S.p.A. (IT) 1997-01-15 — — EP disclosed
US-5567830-A Process for synthesis of acetylenic carbinols COCENSYS, INC. (US) 1996-10-22 — — US disclosed
WO-1995026189-A1 AN IMPROVED METHOD OF SYNTHESIS FOR 6,9-BIS[(2-AMINOETHYL)AMINO]BENZO[g]ISOQUINOLINE-5,10-DIONE AND ITS DIMALEATE SALT BOEHRINGER MANNHEIM ITALIA, S.P.A. (US) 1995-10-05 — — WO disclosed
WO-1994005641-A1 4-SUBSTITUTED 6,9,-BIS (SUBSTITUTED-AMINO) BENZO [g] ISOQUINOLINE-5,10,DIONES THE UNIVERSITY OF VERMONT (US) 1994-03-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222190-A1 1,4-bis-N-oxide azaanthracenediones and the use thereof CCND1, BRCA1, CDKN1A MAOA 967/4885MAOB 904/4885CDC25B 163/4885
US-20260097359-A1 MULTI-TUBULAR ELECTROCHEMICAL CELL FOR TARGET SPECIES SEPARATIONS SLC9A2, SLC9A1, SLC9A3 MAOA 3324/4885MAOB 4144/4885CDC25B 852/4885
US-12458922-B2 Electroactive species and method for electrochemical gas separation LPO, SQOR, QSOX1 MAOA 286/4885MAOB 772/4885CDC25B 2715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.