Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673208 | 1.00 | HTT (0.50) | HTTALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9674680 | 0.86 | ALDH1A1 (0.48) | HTTALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9674684 | 0.86 | ALDH1A1 (0.48) | HTTALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL14466823 | 0.84 | SMN1; SMN2 (0.57) | HTTALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5335075 | 0.81 | HTT (0.59) | HTTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL5335069 | 0.81 | HTT (0.59) | HTTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL5345794 | 0.73 | HTT (0.52) | HTTALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5345792 | 0.73 | HTT (0.52) | HTTALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9673579 | 0.72 | SMN1; SMN2 (0.51) | HTTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL9262044 | 0.71 | SMN1; SMN2 (0.50) | HTTALOX15ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234045-B1 | A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4843068-A | INSECTICIDES, MITICIDES, FUNGICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0234045-A2 | A pyrazole oxime derivative and its production and use | NIHON NOHYAKU CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |