SCHEMBL9673237

SCHEMBL9673237

C=C(c1ccc(C)cc1)c1ccc(N2CCCC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.58
NPC1 O15118 8/20 0.58
RAB9A P51151 8/20 0.58
L3MBTL1 Q9Y468 4/20 0.58
LMNA P02545 4/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
KDM4E B2RXH2 3/20 0.58
KMT2A Q03164 3/20 0.58
MCL1 Q07820 2/20 0.58
MEN1 O00255 2/20 0.58
ALDH1A1 P00352 8/20 0.49
HPGD P15428 4/20 0.49
ALOX15 P16050 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
ADRB1 P08588 1/20 0.48
TP53 P04637 3/20 0.47
TSHR P16473 2/20 0.47
HSD17B10 Q99714 2/20 0.47
STAT1 P42224 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9671475 0.98 MAPT (0.56) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL9673663 0.98 MAPT (0.56) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL10472733 0.90 ALDH1A1 (0.57) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL10472913 0.88 ALDH1A1 (0.60) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL10473961 0.88 ALDH1A1 (0.60) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL327765 0.84 ADRB1 (0.64) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL9672125 0.84 MAPT (0.59) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL611868 0.83 MAPT (0.68) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL7958674 0.83 MAPT (0.51) MAPTNPC1RAB9AL3MBTL1LMNA
SCHEMBL611411 0.82 MAPT (0.53) MAPTNPC1RAB9AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62243652-A None JP disclosed
EP-0242169-B1 DIVINYL COMPOUNDS AND CHROMOGENIC RECORDING MATERIAL PREPARED BY USE THEREOF YAMADA CHEMICAL CO., LTD. (JP) 1992-01-02 EP disclosed
US-4898941-A Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-02-06 US disclosed
US-4808567-A PHOTOSTABILITY, WATERPROOFING YAMADA CHEMICAL CO., LTD. (JP) 1989-02-28 US disclosed
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed
JP-S62243652-A DIVINYL COMPOUND AND COLORING RECORD MATERIAL USING SAME YAMADA CHEM CO LTD 1987-10-24 JP disclosed
EP-0242169-A2 Divinyl compounds and chromogenic recording material prepared by use thereof YAMADA CHEMICAL CO., LTD. (JP) 1987-10-21 EP disclosed