Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050522 | 0.88 | ADRA1A (0.77) | ADRA1APDE4DALDH1A1TSHR | |
| SCHEMBL9673177 | 0.86 | ADRA1A (0.46) | ADRA1APDE4DSOAT1ALDH1A1 | |
| SCHEMBL9674811 | 0.84 | ADRA1A (0.49) | ADRA1APDE4DALDH1A1TSHR | |
| SCHEMBL9672783 | 0.84 | ADRA1A (0.44) | ADRA1APDE4DSOAT1ALDH1A1 | |
| Malotilate SCHEMBL635496 | 0.83 | ADRA1A (1.00) | ADRA1APDE4DTSHR | |
| SCHEMBL9673295 | 0.82 | SOAT1 (0.44) | ADRA1APDE4DSOAT1ALDH1A1TSHR | |
| SCHEMBL9673209 | 0.81 | ADRA1A (0.45) | ADRA1APDE4DALDH1A1TSHR | |
| SCHEMBL9706745 | 0.78 | ADRA1A (0.75) | ADRA1APDE4D | |
| SCHEMBL9672633 | 0.77 | ADRA1A (0.63) | ADRA1APDE4D | |
| SCHEMBL9621031 | 0.76 | ADRA1A (0.55) | ADRA1APDE4DALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |