Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673177 | 0.89 | ADRA1A (0.46) | SOAT1ADRA1APDE4DALDH1A1KMT2A | |
| SCHEMBL8531170 | 0.86 | ADRA1A (0.46) | ADRA1APDE4DALDH1A1KMT2AMEN1 | |
| SCHEMBL9672783 | 0.86 | ADRA1A (0.44) | SOAT1ADRA1APDE4DALDH1A1KMT2A | |
| SCHEMBL9674608 | 0.82 | ADRA1A (0.69) | SOAT1ADRA1APDE4DALDH1A1TSHR | |
| SCHEMBL9621031 | 0.77 | ADRA1A (0.55) | ADRA1APDE4DALDH1A1KMT2AMEN1 | |
| SCHEMBL8385459 | 0.73 | ADRA1A (0.50) | ADRA1APDE4DALDH1A1MAPTKDM4E | |
| SCHEMBL9621035 | 0.71 | ADRA1A (0.57) | ADRA1APDE4DMAPT | |
| SCHEMBL2725876 | 0.70 | ADRA1A (0.46) | ADRA1APDE4D | |
| SCHEMBL28209535 | 0.70 | SOAT1 (0.78) | SOAT1ALDH1A1ALOX15MAPTKDM4E | |
| SCHEMBL8050522 | 0.68 | ADRA1A (0.77) | ADRA1APDE4DALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |