Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581915 | 0.87 | LMNA (0.39) | LMNAPDE10ANOS1 | |
| Hydrochloric Acid SCHEMBL11582940 | 0.84 | LMNA (0.38) | LMNANOS1 | |
| SCHEMBL3670530 | 0.83 | LMNA (0.41) | LMNAPDE10ANOS1 | |
| SCHEMBL20869795 | 0.80 | LMNA (0.39) | LMNAPDE10ANOS1 | |
| SCHEMBL2067816 | 0.79 | LMNA (0.46) | LMNAPDE10ANOS1 | |
| SCHEMBL2284408 | 0.79 | LMNA (0.46) | LMNANOS1 | |
| Hydrochloric Acid SCHEMBL4932899 | 0.77 | LMNA (0.44) | LMNAPDE10A | |
| SCHEMBL5924277 | 0.73 | LMNA (0.46) | LMNANOS1 | |
| SCHEMBL28173266 | 0.69 | HSP90AA1 (0.32) | LMNA | |
| SCHEMBL8003108 | 0.69 | HSP90AB1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003866-A1 | NOVEL 2-DIMETHYLAMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS | NEUROSEARCH A/S (DK) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003866-A1 | NOVEL 2-DIMETHYLAMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS | KCNA7, KCNJ2, KCNN3 | LMNA 1847/4885PDE10A 869/4885NOS1 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.