Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764678 | 1.00 | PSMD10 (0.42) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL9872208 | 0.98 | ALDH1A1 (0.43) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL9872763 | 0.94 | PSMD10 (0.44) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL19386611 | 0.88 | ALDH1A1 (0.44) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL10860607 | 0.88 | STAT3 (0.46) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL17614843 | 0.87 | STAT3 (0.46) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL8863706 | 0.87 | STAT3 (0.46) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL9458218 | 0.87 | STAT3 (0.46) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL7827739 | 0.87 | STAT3 (0.46) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 | |
| SCHEMBL9764712 | 0.87 | STAT3 (0.46) | PSMD10ALDH1A1KMT2ARAB9ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312040-B1 | 2,4-DISUBSTITUTED DERIVATIVES OF TETRAHYDROFURAN | J. URIACH & CIA. S.A. (ES) | 1992-06-03 | — | — | EP | disclosed |
| US-4997843-A | Platelet activating factor, anticoagulants | J URIACH & CIA S.A. (ES) | 1991-03-05 | — | — | US | disclosed |
| EP-0353777-A2 | New 2,5-disubstituted tetrahydrofuran derivatives | J. URIACH & CIA. S.A. (ES) | 1990-02-07 | — | — | EP | disclosed |
| EP-0312040-A2 | 2,4-Disubstituted derivatives of tetrahydrofuran | J. URIACH & CIA. S.A. (ES) | 1989-04-19 | — | — | EP | disclosed |