Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872208 | 0.95 | ALDH1A1 (0.43) | PSMD10STAT3ALDH1A1POLBKMT2A | |
| SCHEMBL9675142 | 0.94 | PSMD10 (0.42) | PSMD10STAT3ALDH1A1POLBKMT2A | |
| SCHEMBL9764678 | 0.94 | PSMD10 (0.42) | PSMD10STAT3ALDH1A1POLBKMT2A | |
| SCHEMBL10860607 | 0.90 | STAT3 (0.46) | PSMD10STAT3ALDH1A1KMT2ARAB9A | |
| SCHEMBL15665928 | 0.87 | STAT3 (0.46) | PSMD10STAT3ALDH1A1POLBKMT2A | |
| SCHEMBL7265145 | 0.86 | TSHR (0.50) | PSMD10STAT3ALDH1A1POLBKMT2A | |
| SCHEMBL29165346 | 0.83 | PSMD10 (0.48) | PSMD10STAT3ALDH1A1POLBKMT2A | |
| SCHEMBL9675663 | 0.83 | PSMD10 (0.43) | PSMD10STAT3ALDH1A1KMT2ARAB9A | |
| SCHEMBL483847 | 0.83 | ALDH1A1 (0.50) | PSMD10STAT3ALDH1A1KMT2ACA12 | |
| SCHEMBL890725 | 0.83 | ALDH1A1 (0.50) | PSMD10STAT3ALDH1A1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070139-A | PLATELET ACTIVATING FACTOR ANTAGONISTS, HYPOTENSIVES | J. URIACH & CIA. S.A. (ES) | 1991-12-03 | — | — | US | disclosed |
| US-4940706-A | 2,4-disubstituted 1,3-dioxolanes and pharmaceutical use | J. URIACH & CIA, S.A. (ES) | 1990-07-10 | — | — | US | disclosed |
| EP-0312041-A2 | 2,4-Disubstituted 1,3-dioxolanes | J. URIACH & CIA. S.A. (ES) | 1989-04-19 | — | — | EP | disclosed |