Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859850 | 0.91 | AGTR1 (0.34) | AGTR1 | |
| SCHEMBL9309363 | 0.91 | EDNRA (0.37) | EDNRAAGTR1 | |
| SCHEMBL9311392 | 0.89 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL9309199 | 0.87 | EDNRA (0.32) | EDNRA | |
| SCHEMBL7300275 | 0.86 | AGTR2 (0.41) | AGTR1 | |
| SCHEMBL9310584 | 0.84 | AGTR1 (0.36) | KDM4ENPSR1HSD17B10AGTR1 | |
| SCHEMBL9309881 | 0.84 | — | — | |
| SCHEMBL7309024 | 0.84 | AGTR1 (0.33) | KDM4ENPSR1HSD17B10EDNRAAGTR1 | |
| SCHEMBL9308209 | 0.83 | AGTR1 (0.39) | EDNRAAGTR1 | |
| SCHEMBL9309904 | 0.82 | MAPK1 (0.36) | KDM4EHSD17B10AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020673-A1 | ANTIHYPOTENSIVE BENZOFURAN DERIVATIVES WITH N-LINKED 1H-IMIDAZOLYLMETHYL-5-CARBOXAMIDE SUBSTITUENTS | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514216-A1 | Antihypotensive benzofuran derivatives with N-linked 1H-imidazolyl-methyl-5-carboxamide substituents | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |