Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715459 | 0.73 | ADAMTS5 (0.33) | ADAMTS5 | |
| SCHEMBL31145024 | 0.72 | BACE1 (0.43) | DUTBACE1 | |
| SCHEMBL10958983 | 0.72 | BACE1 (0.43) | DUTBACE1 | |
| SCHEMBL6527128 | 0.72 | BACE1 (0.38) | DUTBACE1 | |
| SCHEMBL23782284 | 0.71 | GNRHR (0.36) | ADAMTS5 | |
| SCHEMBL7754786 | 0.71 | BACE1 (0.37) | DUTBACE1 | |
| SCHEMBL1247159 | 0.71 | BACE1 (0.37) | DUTBACE1 | |
| SCHEMBL17398862 | 0.71 | ALDH1A1 (0.42) | DUTBACE1 | |
| SCHEMBL5736393 | 0.70 | DUT (0.34) | DUT | |
| SCHEMBL6518418 | 0.70 | CA1 (0.43) | DUTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |