SCHEMBL9675663

SCHEMBL9675663

Cc1ccc(S(=O)(=O)OCCCCOC(=O)Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PSMD10 O75832 1/20 0.43
STAT3 P40763 2/20 0.43
ALDH1A1 P00352 5/20 0.41
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 3/20 0.38
FKBP1A P62942 2/20 0.38
GAA P10253 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
SIRT5 Q9NXA8 1/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP24A1 Q07973 1/20 0.38
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9673458 0.98 PSMD10 (0.42) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL13740848 0.86 PSMD10 (0.44) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL890725 0.85 ALDH1A1 (0.50) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL9872208 0.85 ALDH1A1 (0.43) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL9675142 0.84 PSMD10 (0.42) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL20457293 0.84 PSMD10 (0.42) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL9690800 0.84 NAAA (0.45) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL9764678 0.84 PSMD10 (0.42) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL8484861 0.84 ALDH1A1 (0.48) PSMD10STAT3ALDH1A1CA12CA1
SCHEMBL4951882 0.84 ALDH1A1 (0.48) PSMD10STAT3ALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312040-B1 2,4-DISUBSTITUTED DERIVATIVES OF TETRAHYDROFURAN J. URIACH & CIA. S.A. (ES) 1992-06-03 EP disclosed
US-4997843-A Platelet activating factor, anticoagulants J URIACH & CIA S.A. (ES) 1991-03-05 US disclosed
EP-0312040-A2 2,4-Disubstituted derivatives of tetrahydrofuran J. URIACH & CIA. S.A. (ES) 1989-04-19 EP disclosed