Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31345724 | 0.86 | IDO1 (0.66) | TDP1IDO1NPSR1F10ALPL | |
| SCHEMBL6640558 | 0.86 | IDO1 (0.66) | TDP1IDO1NPSR1F10ALPL | |
| SCHEMBL8417202 | 0.82 | DDAH1 (0.58) | TDP1IDO1F10ALDH1A1KDM4E | |
| SCHEMBL20867740 | 0.82 | IDO1 (0.57) | IDO1F10ALPLALPIALPG | |
| SCHEMBL1083641 | 0.82 | IDO1 (0.49) | TDP1IDO1F10ALPLALPI | |
| SCHEMBL16808069 | 0.81 | L3MBTL1 (0.40) | TDP1IDO1NPSR1F10ALPL | |
| Hydrochloric Acid SCHEMBL23497518 | 0.81 | IDO1 (0.55) | IDO1F10ALPLALPIALPG | |
| Hydrochloric Acid SCHEMBL22228556 | 0.81 | IDO1 (0.55) | IDO1F10ALPLALPIALPG | |
| SCHEMBL9513404 | 0.80 | TSHR (0.47) | TDP1IDO1F10ALDH1A1KDM4E | |
| SCHEMBL13351516 | 0.79 | IDO1 (0.54) | IDO1ALDH1A1KDM4EPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9323153-B2 | Actinic ray-sensitive or radiation-sensitive resin composition, and, actinic ray-sensitive or radiation-sensitive film and pattern forming method, each using the same | FUJIFILM CORPORATION (JP) | 2016-04-26 | — | — | US | disclosed |
| US-9323153-B2 | Actinic ray-sensitive or radiation-sensitive resin composition, and, actinic ray-sensitive or radiation-sensitive film and pattern forming method, each using the same | FUJIFILM CORPORATION (JP) | 2016-04-26 | — | — | US | disclosed |
| US-20150168415-A1 | COMPOUNDS AND METHODS FOR ANALYSIS AND SYNTHESIS OF SACCHARIDE COMPOUNDS | ACADEMIA SINICA (TW) | 2015-06-18 | — | — | US | disclosed |
| US-20150004533-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE SAME | FUJIFILM CORPORATION (JP) | 2015-01-01 | — | — | US | disclosed |
| US-20150004533-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE SAME | FUJIFILM CORPORATION (JP) | 2015-01-01 | — | — | US | disclosed |
| EP-1671972-A1 | Octahydropyrrolo[3,4-c]pyrrole derivatives | Pfizer Limited (GB) | 2006-06-21 | — | — | EP | disclosed |
| US-20060111416-A1 | Octahydropyrrolo[3,4-C]pyrrole derivatives | PFIZER INC. | 2006-05-25 | — | — | US | disclosed |
| EP-1311268-A4 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE ANTIVIRAL AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2004-06-30 | — | — | EP | disclosed |
| CN-1436079-A | Imidazopyridine and imidazopyrimidine antiviral agent | BRISTOL MYERS SQUIBB CO (US) | 2003-08-13 | — | — | CN | disclosed |
| EP-1311268-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6489338-B2 | TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTION. | BRISTOL-MYERS SQUIBB COMPANY | 2002-12-03 | — | — | US | disclosed |
| US-20020016309-A1 | Imidazopyridine and imidazopyrimidine antiviral agents | BRISTOL-MEYERS SQUIBB COMPANY | 2002-02-07 | — | — | US | disclosed |
| WO-2001095910-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111416-A1 | Octahydropyrrolo[3,4-C]pyrrole derivatives | DPYD, PAH, DHPS | TDP1 1015/4885IDO1 806/4885NPSR1 331/4885 |
| US-20150168415-A1 | COMPOUNDS AND METHODS FOR ANALYSIS AND SYNTHESIS OF SACCHARIDE COMPOUNDS | MPI, GPI, FUT6 | TDP1 4340/4885IDO1 2365/4885NPSR1 3475/4885 |
| US-20020016309-A1 | Imidazopyridine and imidazopyrimidine antiviral agents | MAVS, ZC3HAV1, EIF2AK2 | TDP1 1773/4885IDO1 235/4885NPSR1 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.