Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.71 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678564 | 0.89 | POLB (0.57) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL9676149 | 0.88 | POLB (0.64) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL9677274 | 0.88 | POLB (0.67) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL9676475 | 0.84 | POLB (0.59) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL9676868 | 0.81 | POLB (0.58) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL9678530 | 0.80 | POLB (0.55) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL9676874 | 0.79 | NPC1 (0.53) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL13303300 | 0.77 | HTR6 (0.71) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL9677876 | 0.77 | POLB (0.58) | HTR6RIPK1MAPTPOLBMEN1 | |
| SCHEMBL9677282 | 0.76 | RIPK1 (0.55) | RIPK1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |